CIA chief Hunley (Baldwin) convinces a Senate committee to disband the IMF (Impossible Mission Force), of which Ethan Hunt (Cruise) is a key member. Hunley argues that the IMF is too reckless. Now on his own, Hunt goes after a shadowy and deadly rogue organization called the Syndicate.

Mike and Eddie manage to track down the villain responsible for the death of Katie to exact their revenge, but all does not go according to plan in Rio against the backdrop of the World Cup.